abstract：BACKGROUND/AIM:The British Committee for Standards in Haematology currently recommends concomitant splenectomy in children with mild hereditary spherocytosis (HS) undergoing cholecystectomy for symptomatic gallstones. However, splenectomy is associated with a risk of life-threatening infection, particularly in young ch...

journal_title：Archives of disease in childhood

authors： Alizai NK,Richards EM,Stringer MD

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To elucidate the current situation of randomised drug trials involving the paediatric population. METHODS:Systematic review of paediatric randomised controlled trials of medicinal products published in 2007. Three major databases were searched with validated search strategies; Medline, Embase and Cochrane Ce...

journal_title：Archives of disease in childhood

authors： Aripin KN,Choonara I,Sammons HM

更新日期：2010-06-01 00:00:00

abstract：STUDY OBJECTIVES:To present diagnosis and treatment modalities of children with interstitial lung disease associated with frequent or rare surfactant protein C gene (SFTPC) mutation. PATIENTS:Twenty-two children with chronic lung disease associated with SFTPC mutation in a heterozygous form. RESULTS:Mutations located...

journal_title：Archives of disease in childhood

authors： Thouvenin G,Abou Taam R,Flamein F,Guillot L,Le Bourgeois M,Reix P,Fayon M,Counil F,Depontbriand U,Feldmann D,Pointe HD,de Blic J,Clement A,Epaud R

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Children with severe malnutrition (SAM) present to hospital with an array of complications, resulting in high mortality despite adherence to WHO guidelines. Diagnostic resources in developing countries are limited and bedside tests could help identify high-risk children. Dipstick urinalysis is a bedside scre...

journal_title：Archives of disease in childhood

authors： Thuo N,Ohuma E,Karisa J,Talbert A,Berkley JA,Maitland K

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of oral sweet solutions to water or no treatment in infants aged 1-12 months during immunisation. METHODS:Randomised controlled trials (RCTs) were retrieved through internet searches or manual searches of reference lists. Search terms included newborn, infant, pain, sucrose and altern...

journal_title：Archives of disease in childhood

authors： Harrison D,Stevens B,Bueno M,Yamada J,Adams-Webber T,Beyene J,Ohlsson A

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To report the evidence for and challenges to the validity of Sheffield Peer Review Assessment Tool (SPRAT) with paediatric Specialist Registrars (SpRs) across the UK as part of Royal College of Paediatrics and Child Health workplace based assessment programme. DESIGN:Quality assurance analysis, including gen...

journal_title：Archives of disease in childhood

authors： Archer J,McGraw M,Davies H

更新日期：2010-05-01 00:00:00

abstract：AIM:Several studies have suggested a beneficial effect of infant breastfeeding on childhood cognitive function. The main objective was to examine whether duration of breastfeeding and age at introduction of complementary foods are related to cognitive performance in 9- to 10-year-old school-aged children in South India...

journal_title：Archives of disease in childhood

authors： Veena SR,Krishnaveni GV,Srinivasan K,Wills AK,Hill JC,Kurpad AV,Muthayya S,Karat SC,Nalinakshi M,Fall CH

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:To determine the utility of a novel Paediatric Consultation Assessment Tool (PCAT). DESIGN:Developed to measure clinicians' communication behaviour with children and their parents/guardian, PCAT was designed according to consensus guidelines and refined at a number of stages. Volunteer clinicians provided vi...

journal_title：Archives of disease in childhood

authors： Howells RJ,Davies HA,Silverman JD,Archer JC,Mellon AF

更新日期：2010-05-01 00:00:00

abstract：:Necrotising pneumonia in young, previously healthy patients due to Panton-Valentine leucocidin (PVL) producing Staphylococcus aureus has been increasingly recognised. PVL pneumonia is often associated with influenza co-infection and high mortality. This case report describes the successful management of the first docu...

journal_title：Archives of disease in childhood

authors： Obando I,Valderrabanos ES,Millan JA,Neth OW

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:Cochlear implantation in one ear (unilateral implantation) has been the standard treatment for severe-profound childhood deafness. We assessed whether cochlear implantation in both ears (bilateral implantation) is associated with better listening skills, higher health-related quality of life (health utility) ...

journal_title：Archives of disease in childhood

authors： Lovett RE,Kitterick PT,Hewitt CE,Summerfield AQ

更新日期：2010-02-01 00:00:00

abstract：:Fine needle aspiration biopsy (FNAB) offers a simple outpatient technique for specimen collection in child tuberculosis suspects with peripheral lymphadenopathy. To perform FNAB with mycobacterial culture on an outpatient basis requires use of a sterile transport medium to facilitate bedside inoculation, maintain orga...

journal_title：Archives of disease in childhood

authors： Wright CA,Bamford C,Prince Y,Vermaak A,Hoek KG,Marais BJ,Warren RM

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Obesity is considered a polygenic and multifactorial disorder and different single nucleotide polymorphisms (SNP) are involved. Studies concerning their impact on weight loss in lifestyle intervention are scarce. METHODS:The effect of two different SNP (INSIG2: rs7566605, FTO: rs9939609) was analysed on the ...

journal_title：Archives of disease in childhood

authors： Reinehr T,Hinney A,Toschke AM,Hebebrand J

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To assess psychological and social functioning and health related quality of life and its early determinants in children born with congenital diaphragmatic hernia (CDH). DESIGN:Cross-sectional follow-up study. SETTING:Outpatient clinic of a tertiary care hospital. PARTICIPANTS:33 CDH survivors aged 6-16 ye...

journal_title：Archives of disease in childhood

authors： Peetsold MG,Huisman J,Hofman VE,Heij HA,Raat H,Gemke RJ

更新日期：2009-11-01 00:00:00

abstract：:We describe two cases of a non-epileptic florid movement disorder presenting as status epilepticus. Both patients presented with florid jerking of the limbs and eyes. Convulsive status epilepticus related to presumed meningitis or encephalitis was suspected in both cases. The patients received treatment for seizures, ...

journal_title：Archives of disease in childhood

authors： Haden SV,McShane MA,Holt CM

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To study the effect of modified polyunsaturated fatty acid (PUFA) profiles of complementary food on long-chain (LC) PUFA composition in healthy infants. DESIGN:Double blinded, randomised, controlled intervention trial. SETTING:Dortmund, Germany. PATIENTS:Free-living sample of healthy term infants. METHODS...

journal_title：Archives of disease in childhood

authors： Schwartz J,Dube K,Sichert-Hellert W,Kannenberg F,Kunz C,Kalhoff H,Kersting M

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Cerebral venous sinus thrombosis (CVST) in children is associated with a high incidence of serious morbidity and mortality. The presenting features are variable. It can be diagnostically challenging and the optimal treatment is uncertain. AIM:To describe the features of a series of children with CVST treate...

journal_title：Archives of disease in childhood

authors： Mallick AA,Sharples PM,Calvert SE,Jones RW,Leary M,Lux AL,O'Callaghan FJ,Osborne JP,Patel JS,Prendiville AT,Renowden S,Jardine PE

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:A tailor-made serogroup B outer membrane vesicle vaccine was evaluated in the context of a serogroup B meningococcal epidemic dominated by Neisseria meningitidis strain B:4:P1.7b,4. OBJECTIVE:To determine the safety, reactogenicity and immunogenicity in infants aged 6-8 months of a meningococcal B vaccine d...

journal_title：Archives of disease in childhood

authors： Jackson C,Lennon DR,Sotutu VT,Yan J,Stewart JM,Reid S,Crengle S,Oster P,Ypma E,Aaberge I,Mulholland K,Martin DR

更新日期：2009-10-01 00:00:00

abstract：AIMS:To explore the clinical course of children with "single kidney" (defined as either a solitary or single functioning kidney) with reference to renal function (glomerular filtration rate (GFR) and proteinuria), body height and particularly sonomorphological features. PATIENTS AND METHODS:This retrospective monocent...

journal_title：Archives of disease in childhood

authors： Spira EM,Jacobi C,Frankenschmidt A,Pohl M,von Schnakenburg C

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Most babies receive at least some formula milk. Variations in formula-feeding practices can have both short- and long-term health consequences. The literature on parents' experiences of bottle-feeding was systematically reviewed to understand how formula-feeding decisions are made. METHODS:Relevant English-l...

journal_title：Archives of disease in childhood

authors： Lakshman R,Ogilvie D,Ong KK

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:To assess the effect of altitude and acclimatisation on cardiorespiratory function and well-being in healthy children. METHODS:A daily symptom diary, serial measurements of spirometry, end-tidal carbon dioxide (etCO(2)) and daytime and overnight pulse oximetry (SpO(2)), were undertaken at sea level and alti...

journal_title：Archives of disease in childhood

authors： Scrase E,Laverty A,Gavlak JC,Sonnappa S,Levett DZ,Martin D,Grocott MP,Stocks J

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:Risk of childhood asthma is increased in children with recurrent otitis media. This may be associated with recurrent respiratory tract infections in these children, but the role of adenoidectomy, a frequent operation during childhood, is unknown. Therefore, the role of adenoidectomy in the development of atop...

journal_title：Archives of disease in childhood

authors： Mattila PS,Hammarén-Malmi S,Pelkonen AS,Malmberg LP,Mäkelä MJ,Saxen H,Tarkkanen J

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Therapeutic hypothermia, a safe and effective treatment for neonatal encephalopathy in an intensive care setting, is not available in low-resource settings. Aims/ METHODS:To assess two low-tech, low-cost cooling devices for use in low-resource settings: (i) commercially available water bottles filled with t...

journal_title：Archives of disease in childhood

authors： Iwata S,Iwata O,Olson L,Kapetanakis A,Kato T,Evans S,Araki Y,Kakuma T,Matsuishi T,Setterwall F,Lagercrantz H,Robertson NJ

更新日期：2009-05-01 00:00:00

abstract：AIMS:To describe the clinical features, diagnosis and management of children with tuberculosis in the United Kingdom and Republic of Ireland. METHODS:Cases of culture-confirmed and clinically diagnosed tuberculosis were reported to the British Paediatric Surveillance Unit from December 2003 to January 2005. RESULTS:3...

journal_title：Archives of disease in childhood

authors： Teo SS,Riordan A,Alfaham M,Clark J,Evans MR,Sharland M,Novelli V,Watson JM,Sonnenberg P,Hayward A,Moore-Gillon J,Shingadia D,British Paediatric Surveillance Unit Childhood Tuberculosis Study Group.

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To examine and compare the characteristics of food protein-induced enterocolitis syndrome (FPIES) caused by rice and cow's milk/soy. DESIGN:Retrospective study of children presenting with FPIES to the Children's Hospital at Westmead, NSW, Australia, over a 16-year period. RESULTS:There were 14 children with...

journal_title：Archives of disease in childhood

authors： Mehr SS,Kakakios AM,Kemp AS

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Acute respiratory infections (ARI) cause 3 million deaths in children worldwide each year. Most of these deaths occur from pneumonia in developing countries, and hypoxaemia is the most common fatal complication. Simple and adaptable indications for oxygen therapy are important in the management of ARI. The c...

journal_title：Archives of disease in childhood

authors： Subhi R,Smith K,Duke T

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To describe the recent trends in demographic, clinical and microbiological characteristics and outcome of treatment in paediatric cases of tuberculosis. DESIGN:National surveillance study. SETTING:England and Wales. PATIENTS:All children under the age of 16 years reported with tuberculosis to the national ...

journal_title：Archives of disease in childhood

authors： Abubakar I,Laundy MT,French CE,Shingadia D

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Sudden Infant Death Syndrome (SIDS) is associated with prone sleeping, and circulatory failure has been hypothesised to be a factor in the fatal event. We aimed to determine the effect of prone sleeping on heart rate (HR) and blood pressure (BP) control over the first 6 months of life. SUBJECTS:Term infants ...

journal_title：Archives of disease in childhood

authors： Yiallourou SR,Walker AM,Horne RS

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Some victims of sudden infant death syndrome (SIDS) are found with their heads covered with bedclothes, but the significance of this is uncertain. The aim of this review is to describe the prevalence of head covering, the magnitude of the risk and how far the suggested causal mechanisms agree with current ep...

journal_title：Archives of disease in childhood

authors： Blair PS,Mitchell EA,Heckstall-Smith EM,Fleming PJ

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To examine the efficacy and safety of torasemide in children with chronic heart failure (HF). METHODS:102 children with chronic HF who had received oral torasemide were analysed. Of these, 62 (de novo group) were newly diagnosed as having HF and were given torasemide as a diuretic. The remaining 40 (replacem...

journal_title：Archives of disease in childhood

authors： Senzaki H,Kamiyama M,Masutani S,Ishido H,Taketazu M,Kobayashi T,Katogi T,Kyo S

更新日期：2008-09-01 00:00:00

abstract：:Four child-protection scenarios were sent to 200 named/designated and non-named/non-designated doctors. The respondents judged each scenario as abuse or accident and indicated their degree of certainty. There was a 71% response rate. There were no significant differences in judgement or degrees of certainty of judgeme...

journal_title：Archives of disease in childhood

authors： Power S

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:Assays based on interferon gamma (IFNgamma) are an exciting new development for screening for latent tuberculosis infection (LTBI) in adults, but there are limited data on their effectiveness in children. Nevertheless new National Institute for Health and Clinical Excellence (NICE) guidelines recommend their ...

journal_title：Archives of disease in childhood

authors： Taylor RE,Cant AJ,Clark JE

更新日期：2008-03-01 00:00:00

abstract：:In acute paediatrics, overtreatment and overdiagnosis is encountered in threshold and developed countries. The reason for overtreatment may be similar in the two settings, namely the mere availability of invasive procedures, which may lead to their inappropriate use. Physiological healing processes should be integrate...

journal_title：Archives of disease in childhood

authors： Frey B

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To determine whether the presence of in vitro penicillin-resistant Streptococcus pneumoniae increases the risk of clinical failure in children hospitalised with severe pneumonia and treated with penicillin/ampicillin. DESIGN:Multicentre, prospective, observational study. SETTING:12 tertiary-care centres in ...

journal_title：Archives of disease in childhood

authors： Cardoso MR,Nascimento-Carvalho CM,Ferrero F,Berezin EN,Ruvinsky R,Camargos PA,Sant'anna CC,Brandileone MC,de Fátima P March M,Feris-Iglesias J,Maggi RS,Benguigui Y,CARIBE Group.

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The use of intravenous immunoglobulin (IVIG) is well established as an initial therapy for Kawasaki disease (KD), but treatment for IVIG-resistant KD remains uncertain AIM:To analyse the effects of intravenous methylprednisolone (IVMP) pulse therapy compared with additional IVIG in IVIG-resistant patients. ...

journal_title：Archives of disease in childhood

authors： Furukawa T,Kishiro M,Akimoto K,Nagata S,Shimizu T,Yamashiro Y

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:To assess factors associated with granting of the Disability Living Allowance (DLA) for Down syndrome. DESIGN:Cross-sectional survey. SETTING:Families with a child with Down syndrome enrolled in a community-based trial of vitamin supplementation. PARTICIPANTS:156 children with trisomy 21 (59% male, 20% no...

journal_title：Archives of disease in childhood

authors： Ellis J,Logan S,Pumphrey R,Tan HK,Henley W,Edwards V,Moy R,Gilbert R

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To examine the experiences and concerns of young people and their parents regarding the management of medication for asthma or diabetes whilst at school. METHODS:Face-to-face semi-structured interviews were conducted with 69 young people aged 8-15 years (43 with asthma and 26 with diabetes) and their parents (...

journal_title：Archives of disease in childhood

authors： Newbould J,Francis SA,Smith F

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of nasopharyngeal (NP) carriage of pneumococcus (Streptococcus pneumoniae) and describe the antibiotic resistance patterns and serotypes in young children attending group day care in London. DESIGN AND SUBJECTS:Cross-sectional survey of attendees at a sample of registered child day...

journal_title：Archives of disease in childhood

authors： Roche A,Heath PT,Sharland M,Strachan D,Breathnach A,Haigh J,Young Y

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Chronic abdominal pain (CAP) is common among schoolchildren, but risk factors for its onset are still largely unknown. AIMS:To determine the frequency of onset of CAP in schoolchildren and investigate risk factors for its development. METHODS:1411 schoolchildren aged 11-14 years were recruited from schools...

journal_title：Archives of disease in childhood

authors： El-Metwally A,Halder S,Thompson D,Macfarlane GJ,Jones GT

更新日期：2007-12-01 00:00:00

abstract：:You can't teach old dogs new tricks. Teaching middle-aged dogs new tricks is hard enough. They tend to stick to particular styles of attacking the postman that over the years have proved pretty reliable, often choosing to ignore new findings, or simply failing to keep up with progress in current discussions on, say, t...

journal_title：Archives of disease in childhood

authors： Cameron D

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:To assess the efficacy and safety of polyethylene glycol 3350 plus electrolytes (PEG+E) for the treatment of chronic constipation in children. DESIGN:Randomised, double blind, placebo controlled crossover trial, with two 2-week treatment periods separated by a 2-week placebo washout. SETTING:Six UK paediat...

journal_title：Archives of disease in childhood

authors： Thomson MA,Jenkins HR,Bisset WM,Heuschkel R,Kalra DS,Green MR,Wilson DC,Geraint M

更新日期：2007-11-01 00:00:00